Drug Standards
Sigma Aldrich Fine Chemicals Biosciences Arabinose United States Pharmacopeia (USP) Reference Standard | 5328-37-0 | MFCD00135866 | 50MG
Arabinose United States Pharmacopeia (USP) Reference Standard | Mol Wt: 150.13 | 5328-37-0 | MFCD00135866 | 50MG
Sigma Aldrich Fine Chemicals Biosciences Glyceryl tridecanoate >=99% (GC) | 621-71-6 | MFCD00036239 | 5G
Glyceryl tridecanoate >=99% (GC) | Purity: >=99% (GC) | Mol Wt: 554.84 | 621-71-6 | MFCD00036239 | 5G
Sigma Aldrich Fine Chemicals Biosciences Promethazine Related Compound B United States Pharmacopeia (USP) Reference Standard | 5568-90-1 | 25MG
Promethazine Related Compound B United States Pharmacopeia (USP) Reference Standard | Mol Wt: 320.88 | 5568-90-1 | 25MG
Sigma Aldrich Fine Chemicals Biosciences Spirulina United States Pharmacopeia (USP) Reference Standard | 724424-92-4 | 2X100MG
Spirulina United States Pharmacopeia (USP) Reference Standard | 724424-92-4 | 2X100MG
Medchemexpress LLC Fostamatinib | 901119-35-5 | 99.7% | 25 MG
Fostamatinib is an oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor. It also inhibits Lyn and Lck, playing a role in various cellular pathways. This product is a solid form of Fostamatinib with high purity, suitable for laboratory research.
- Oral proagent of active compound R406
- Competitive Syk/FLT3 inhibitor
- Also inhibits Lyn and Lck
- High purity of 99.7%
- Recommended storage for powder at -20°C for 3 years or 4°C for 2 years
- Recommended storage for in-solvent at -80°C for 1 year or -20°C for 6 months
- Shipped at room temperature for less than 2 weeks
Medchemexpress LLC Tenofovir exalidex | 911208-73-6 | 99.8% | 569.72 | 10 MG
Tenofovir exalidex (CMX-157) is a lipid conjugate of the acyclic nucleotide analog Tenofovir, active against both wild-type and antiretroviral drug-resistant HIV strains. It also demonstrates antiviral activity against HBV. This compound is orally available and shows no apparent toxicity.
- Effective against multidrug nucleoside/nucleotide analog-resistant viruses.
- Active against all major subtypes of HIV-1 and HIV-2.
- Orally available with no apparent toxicity.
Apexbio Technology LLC MDV3100 (Enzalutamide) 915087-33-1 25mg
MDV3100 (Enzalutamide) is a nonsteroidal androgen receptor (AR) antagonist developed as a second-generation inhibitor for prostate cancer research Structurally distinct from earlier AR antagonists such as bicalutamide it exhibits high affinity binding to the androgen receptor ligand-binding domain thereby blocking AR activation steps Specifically it inhibits androgen binding nuclear translocation of the AR and AR-DNA interaction Preclinical studies in prostate cancer cell lines with AR gene amplification including VCaP have indicated that MDV3100 can induce apoptosis MDV3100 serves as a research tool for investigating androgen receptor-mediated pathways and cellular processes in prostate cancer models
Apexbio Technology LLC Lenalidomide (CC-5013) 191732-72-6 500mg
Lenalidomide (CC-5013) a structural analog of thalidomide is a synthetic small-molecule agent exhibiting anti-tumor properties primarily through immune modulation and antiangiogenic activities Mechanistically lenalidomide promotes the activation of immune functions enhances expression of costimulatory molecules on leukemia lymphocytes and restores immunoglobulin synthesis thereby augmenting humoral immune responses Additionally it improves T cell interactions leading to restored immunological synapse formation and function Current research applications involve investigating lenalidomide s therapeutic potential in multiple myeloma myelodysplastic syndrome (MDS) chronic lymphocytic leukemia (CLL) and other lymphoproliferative disorders including non-Hodgkin lymphoma (NHL)
Apexbio Technology LLC Ivermectin B1a(Synonyms: Ivermectin, 22,23-Dihydroavermectin B1a, Avermectin B1a, MK-933, Stromectol, Mectizan), 5mg, CAS: 71827-03-7.
Ivermectin B1a (CAS 71827-03-7) is the primary constituent ( 80%) of the antiparasitic macrocyclic lactone ivermectin Its pharmacological effects originate from selective interaction with glutamate-gated chloride ion channels prevalent in neurons and pharyngeal muscles of nematodes This binding induces durable chloride influx causing sustained hyperpolarization or depolarization resulting in neuromuscular paralysis Ivermectin displays potent antiparasitic efficacy (EC 104 nM) and is clinically significant in treating human onchocerciasis reducing symptoms associated with the infection
Sigma Aldrich Fine Chemicals Biosciences Methsuximide United States Pharmacopeia (USP) Reference Standard | 77-41-8 | 500MG
Methsuximide United States Pharmacopeia (USP) Reference Standard | Mol Wt: 203.24 | 77-41-8 | 500MG
Sigma Aldrich Fine Chemicals Biosciences Camphor United States Phar1G
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Selleck Chemical LLC Voriconazole S1442-10mM/1mL
Voriconazole is a new triazole derivative similar to fluconazole and itraconazole that acts by inhibiting fungal cytochrome P-450-dependent 14-alpha-sterol demethylase-mediated synthesis of ergosterol
Sigma Aldrich Fine Chemicals Biosciences Cefotaxime Related Compound E United States Pharmacopeia (USP) Reference Standard | 66340-33-8 | 15MG
Cefotaxime Related Compound E United States Pharmacopeia (USP) Reference Standard | Mol Wt: 395.41 | 66340-33-8 | 15MG
Apexbio Technology LLC Mesalamine 89-57-6 500mg
Mesalamine (89-57-6) is a small-molecule inhibitor targeting the I B kinase (IKK) signaling pathway It is designed to modulate the inflammatory response thereby regulating the NF- B pathway and the expression of pro-inflammatory mediators Mesalamine exerts its biological activity primarily through inhibition of cytokine-mediated activation of the NF- B pathway Based on these pharmacological properties mesalamine holds research potential in studies of inflammatory signaling cascades autoimmune conditions and related inflammatory disorders
Medchemexpress LLC Lenalidomide | 191732-72-6 | 99.94% | 25 MG
Lenalidomide (CC-5013) is a derivative of Thalidomide that acts as a molecular glue and is an orally active immunomodulator. It functions as a ligand of ubiquitin E3 ligase cereblon (CRBN), leading to the selective ubiquitination and degradation of lymphoid transcription factors IKZF1 and IKZF3 by the CRBN-CRL4 ubiquitin ligase.
- Inhibits growth of mature B-cell lymphomas, including multiple myeloma.
- Induces IL-2 release from T cells.
- Stimulates T cell proliferation, IFN-γ, and IL-2 production.
- Inhibits pro-inflammatory cytokines (TNF-α, IL-1, IL-6, IL-12) and elevates anti-inflammatory cytokine IL-10 from human PBMCs.
- Downregulates IL-6 production and augments myeloma cell apoptosis.
- Functions as a molecular glue between human E3 ubiquitin ligase cereblon and CKIα.
- Induces ubiquitination and degradation of this kinase, killing leukemic cells by p53 activation.